Adenosine Receptors in Neurodegenerative Diseases covers the role of adenosine receptors in brain function, also focusing on related methodologies and perspectives in therapeutics. The book provides an up-to-date overview by the best specialists in the field, helping readers consider the importance of adenosine and expand the global impact and visibility of adenosine research in the CNS field. Chapters include adenosine biology and signaling, gene regulation, control of motor function, and novel adenosine-based therapies in the CNS. It is an ideal resource for researchers, advanced graduate students, clinicians, and industry scientists working in the fields of clinical neuroscience and molecular and cellular neuroscience. Comprehensive reference that details adenosine receptors in neurodegenerative disorders, with details on brain function and possible therapeuticsGives insights on how these receptors modulate the neurodegenerative outcomes in different disordersEdited by two of the leading researchers in the field regarding adenosine role in the brain in aging and neurodegenerative conditions INDICE: Section I. Physiology 1. Physiology: Adenosine receptor biology in the CNS 2. Physiology: Adenosine signaling throughout development 3. Physiology: Influence of adenosine on synaptic excitability 4. Physiology: Regulation of synaptic transmission by adenosine at the neuromuscular junction 5. Physiology: Gene-regulation of adenosine A2A receptors in the central nervous system Section II. Pathology 6. Pathology: Sleep, adenosine, and neurodegeneration 7. Pathology: Neuronal vs. glial cell contribution to adenosine A2A receptor-induced neurodegeneration 8. Pathology: Adenosine and oxygen/glucose deprivation in the brain 9. Pathology: Adenosine receptors and memory disorders 10. Pathology: Control of motor function by adenosine A2A receptors in Parkinson's and Huntington's disease 11. Pathology: Adenosine receptors oligomers in Parkinson's disease 12. Pathology: Adenosine control of striatal function - implications for the treatment of apathy in basal ganglia disorders 13. The road less travelled - future perspectives
- ISBN: 978-0-12-803724-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 300
- Fecha Publicación: 01/04/2017
- Nº Volúmenes: 1
- Idioma: Inglés