The field of hematopoietic stem cell transplantation has undergone both evolutionary and dramatic changes over the past 25 years. This is evident by the fact that the term hematopoietic stem cell transplantation has effectively replaced the older term, bone marrow transplantation, due to the diverse source of hematopoietic cells that are employed for transplantation. Some of the most significant advances in hematopoietic stem cell transplantation have occurred inthe past decade, as our understanding of stem cell biology, hematopoiesis, and immunology have increased. Alternative sources of stem cells, including those from unrelated donors and cord blood, the utilization of less toxic non-myeloablative and reduced-intensity conditioning regimens prior to transplant, andsignificantly improved supportive care measures have made hematopoietic stem cell transplantation available to greater numbers of patients. Written by leading experts in the field of hematopoietic stem cell transplantation Serves as a reference text for those actively involved in research and clinical practiceof hematopoietic stem cell transplantation Provides a current and succinct overview for laboratory scientists, oncologists, hematologists, fellows, residents and medical students in this field INDICE: From the contents Principles and overview of allogeneic hematopoietic stem cell transplantation.- Principles and overview of autologous hematopoietic stem cell transplantation.- Natural killer cell activity and killer immunoglobulin-like receptors in hematopoietic stem cell transplantation.- Advancement and clinical implications of HLA typing in allogeneic hematopoietic stem cell transplantation.- Immunogenomics and proteomics in hematopoietic stem cell transplantation.- Clinical implications of immune reconstitution following autologous and allogeneic hematopoietic stem cell transplantation.- T-regulatory cells and T cell cytokines in hematopoietic stem cell transplantation.- Understanding and enhancing the graft-versus-leukemia effect after hematopoietic stem cell transplantation.- Non-myeloablative and reduced-intensity allogeneic hematopoietic stem cell transplantation.- Cord blood transplantation.- Bone marrow and peripheral blood stem cell transplantation from unrelated donors.
- ISBN: 978-0-387-78579-0
- Editorial: Springer
- Encuadernacion: Cartoné
- Páginas: 480
- Fecha Publicación: 01/12/2008
- Nº Volúmenes: 1
- Idioma: Inglés