Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers. Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies. Lists natural agents, including nutraceuticals, and their effects on normal or tumor genomeAddresses various epigenetic systems and mechanisms in the regulation and support of the mammalian genomeDiscusses how various parts of dietary phytochemicals can influence or modify epigenetic mechanisms in several types of cancer INDICE: Section I: Molecular Epigenetic Targets of Natural products 1. Genetic and epigenetic targets of natural product anticancer agents 2. The role of microRNAs in cancer: influence of nutrient crosstalk 3. Epigenetic impact of dietary isothiocyanates in cancer chemoprevention 4. Epigenetic effects of green tea polyphenols in cancer 5. Epigenetic effects of curcumin in cancer 6. Epigenetic effects of resveratrol in cancer 7. Emerging chemopreventive agents as epigenetic modifiers Section II: Organ Specific Epigenetic Targets of Natural products 1. Epigenomics of ovarian cancer and its chemoprevention 2. Dietary factors and epigenetic regulation for prostate cancer prevention 3. The epigenetics of colorectal cancer 4. The role of epigenetic changes and protection by phytochemicals in breast cancer 5. Epigenetics in urological cancers and chemoprevention treatment approaches 6. Natural products as epigenetic modifiers in the treatment of lung cancer 7. Epigenetic cancer prevention mechanism in skin cancer Section III: Miscellaneous 1. Research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs 2. Epigenetic alterations in cancer and personalized cancer treatment with phytochemicals
- ISBN: 978-0-12-812494-9
- Editorial: Academic Press
- Encuadernacion: Cartoné
- Páginas: 442
- Fecha Publicación: 10/12/2018
- Nº Volúmenes: 1
- Idioma: Inglés