Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods

Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Methods, Second Edition reveals how medicinal chemistry can play a direct role in addressing this issue. After providing essential context on the growth of green chemistry in relation to drug discovery, the book identifies a range of practical techniques and useful insights, revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. Drawing on the knowledge of a global experts, the book encourages the growth of green medicinal chemistry, and supports medicinal chemists, drug discovery researchers, pharmacologists, and more. This volume covers synthesis methods following green chemistry principles, contributing to sustainability by saving energy, using lesser toxic reagents/solvents/catalysts and environmentally benign sources, including plants and agricultural materials. Highlights the need for the adoption of sustainable and green chemistry pathways in drug developmentReveals risk factors associated with the drug development process and the ways sustainable approaches can help address these factorsIdentifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability INDICE: Nanotechnology 1. Nanocatalyzed Organic Transformations for Synthesis of Drug-Like Small Molecules With Medicinally Privileged Heterocycles 2. Nano Based Drug Delivery Of Anticancer Agents 3. Green Synthesis of silver nanoparticles for Antibacterial properties 4. Green Synthesis of Nanoparticles And Nanocomposites: Medical Aspect 5. Nanomaterials Mediated Synthesis Of ?-Lactams and Exploration Of Their Enhanced Biological Activities: Recent Advances Combinatorial Chemistry 6. Green Combinatorial Chemistry in Medicinal Science 7. Combinatorial Chemistry in Cancer Drug Discovery Energy 8. The Use of Ultrasound in Drug Synthesis: A Sustainable Method 9. Solar-powered Chemistry: New Catalytic Solutions for a Greener Planet 10. Photocatalytic Reactions for the Synthesis and Derivatization of Pharmaceutically Significant Heterocycles 11. Visible light-induced dye degradation potential of green synthesized Nanoparticles: An approach towards polluted water treatment 12. Green Synthetic Approach for Biologically Relevant Heterocyclic Compounds By Using Ball Mill 13. Synthesis of Natural Products by Photochemistry 14. Recent Magneto/Electrochemical/Bio-sensors and Analytical Approaches to Detect ß-Lactam Antibiotics in Food and Environment Methods and Synthesis 15. Use of Sustainable Organic Transformations in the Construction of Heterocyclic Scaffolds 16. Diverse Synthesis of Medicinally Active Steroids 17. Solvent-Less Reactions: Green and Sustainable Approaches in Medicinal Chemistry 18. Versatile Thiosugars in Medicinal Chemistry Microwave-Induced Chemistry 19. Microwave-Assisted Synthesis of Anti-tubercular Agents: A Novel Approach 20. Microwave-Induced Synthesis as a Part of Green Chemistry Approach for Novel Anti-inflammatory agents Computers in Drug Discovery 21. Dipole Moment Studies on Beta Lactams 22. Computational Approaches For Development Of Anti-Covid 19 Agents 23. Dipole Moment in Medicinal Research: Green and Sustainable Approach 24. Computational Methods and Tools for Sustainable and Green Approaches in Drug Discovery

• ISBN: 978-0-443-16164-3
• Editorial: Elsevier
• Encuadernacion: Rústica
• Páginas: 656
• Fecha Publicación: 06/06/2024
• Nº Volúmenes: 1
• Idioma: Inglés