Green Approaches in Medicinal Chemistry for Sustainable Drug Design: Applications
Banik, Bimal
Sustainable and Green Approaches in Medicinal Chemistry: Applications, Second Edition reveals essential context on the growth of green chemistry in relation to drug discovery, identifying a broad range of practical techniques and useful insights and revealing how medicinal chemistry techniques can be used to improve efficiency, mitigate failure, and increase the environmental benignity of the entire drug discovery process. The book encourages the growth of green medicinal chemistry and supports medicinal chemists, drug discovery researchers, pharmacologists, and all those in related fields across both academia and industry in integrating these approaches into their own work. This volume includes the development of nanoparticles and nanocomposites, as well as the application of ultrasound and microwave-induced methods; studies solventless synthesis; defines the role of steroids; studies reactions in aqueous solution; identifies enzyme-mediated reactions; investigates ionic liquids and deep eutectic solvents; explores natural products; investigates solid supports; realizes the effects of salts; focuses on combinatorial chemistry; develops one-pot methods; analyzes multi-component reactions; investigates dipole moment values; and examines computer-assisted methods. Highlights the need for adoption of sustainable and green chemistry pathways in drug developmentReveals risk factors associated with the drug development process and the ways sustainable approaches can help address theseIdentifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability INDICE: Chemical Catalysis1. Green Metal-Catalyzed Reactions Under Sustainable Conditions Towards Medicinally Potent Biomolecules2. Graphene Oxide and Modified Graphene Oxide-Mediated Synthesis of Medicinally Active Compounds3. Organocatalytic Cycloaddition Reaction: A Gateway for Molecular ComplexityBiocatalysis4. Baker's Yeast-Induced Synthesis of Medicinally Important Compounds5. New Methods for the Manufacturing of Pharmaceuticals and Their Intermediates Using LipaseGreen Solvents6. Green Synthesis of Biologically Active Pyrroles and Related Substrates via C-H Bond Functionalization7. Ionic Liquids in Pharmaceutics and Bioanalytics8. Synthesis of Bioactive Heterocyclic Compounds Using Green Solvents9. Reactions in Water: Synthesis of Biologically Active CompoundsGreen Chemistry10. Sustainable Green Technologies for Synthesis of Potential Drugs Targeted towards Tropical Diseases11. Clay-Mediated Synthesis of Biologically Active Molecules: Green and Sustainable Approaches12. The Role of Ionic Liquid in Medicinal ChemistryMedicinal Chemistry13. Green Chemistry for the Synthesis of Sulfur containing Compounds with Medicinal Properties14. Sustainable green approaches for synthesis of bio-active flavonoids as cardio-protective and anticancer drug agents15. Polysaccharide-derived hydrogels: An approach towards cancer16. Environmental Benign Pathways for the Synthesis of Medicinally Relevant Heterocycles17. Utilization of medicinally important plants as antidiabetic medicines in a sustainable manner18. One-Pot Synthesis of Biologically Active Oxazole, Iso-oxazole, and Pyranopyazoles-An Overview19. Green synthesis of Organometallic Compounds and their Medicinal aspects20. Biologically active macrocycles in medicine21. Green Synthesis and Biological Evaluation of Anticancer Drugs22. Green Chemistry and Synthetic Approaches in the Development of Antidepressant and Antipsychotic agents23. Organocatalyzed multi-component synthesis of densely functionalized bioactive pyridine derivatives24. Multicomponent reaction strategy to heterocyclic compounds in anticancer drug design25. Recent Advances in Asymmetric Synthesis of ß-Lactams
- ISBN: 978-0-443-16166-7
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 698
- Fecha Publicación: 30/05/2024
- Nº Volúmenes: 1
- Idioma: Inglés