Seldin and Giebischs The Kidney: Physiology & Pathophysiology

A classic nephrology reference for over 25years, Seldin & Giebisch's The Kidney, is the acknowledged authority on renal physiology and pathophysiology. In this 5th edition, such new and powerful disciplines as genetics and cell biology have been deployed to deepen and widen further the explanatory framework. Not only have previous chapters been extensively updated, but new chapters have been added to incorporate additional disciplines. Individual chapters, for example, now provide detailed treatment of the significance of cilia; the role of stem cells is now given special consideration. Finally, there has been a significant expansion of the section of pathophysiology, incorporating the newer findings of cell biology and genetics. If you research the development of normal renal function or the mechanisms underlying renal disease, Seldin & Giebisch's The Kidney is your number one source for information. Offers the most comprehensive coverage on the market of fluid and electrolyte regulation and dysregulation in 85 completely revised chapters and 10 new chapters.Includes 4sections, 62 chapters, devoted to regulation and disorders of acid-base homeostasis, and epithelial and nonepithelial transport regulation. Includes foreword by Donald Seldin and Gerhard Giebisch, world renowned names in nephrology and editors of the previous three editions. INDICE: Section 1: Epithelial and Nonepithelial Transport and Regulation 1 Epithelial Cell Structure and Polarity Michael Caplan 2 Mechanisms of Ion Transport Across Cell Membranes & Epithelia Luis Reuss and Guillermo Altenberg 3 Renal Ion-Translocating AT Phases: The P-Type Family Eric Feraille 4 Mechanisms of Water Transport Across Cell Membranes & Epithelia Luis Reuss and Guillermo Altenberg 5 Cell Volume Control Florian Lang 6 Soute Transport, Energy Consumption, and Production in the Kidney Hitoshi Endou and Takashi Sekine 7 Electrophysiological Analysis of Transepithelial Transport Lawrence G. Palmer and Henry Sackin 8 Ion Channels and Electro-physiological Properties of Transport James Stockand 9 Exchange of Fluid and Solutes Across Microvascular Walls C. Charles Michel 10 External Balance of Electrolytes and Acids and Alkali Man S. Oh 11 Cilium Bradley Yoder 12 Inter-cellular Junctions Alan S. L. Yu, Jano Peti-Perterdi, Fiona Hanner 13 Principles of Cell Signaling Lloyd Cantley 14 Scaffolding Proteins in Transport Regulation Paul A. Welling 15 The Renin-Angiotensin System Thomas M. Coffman 16 Neural Control of Renal Function Ulla C. Kopp and EJ Johns 17 Eicosanoids and the Kidney Matthew Breyer, Raymond C. Harris, Richard M. Breyer 18 Extracellular Nucleotides and Renal Function Robert J. Unwin and David Shirley 19 Paracrine Regulation of Renal Function by Dopamine Pedro Jose Section 2: Structural and Functional Organization of the Kidney 20 Structural Organization of the Mammalian Kidney Wilhelm Kriz and Brigitte Kaissling 21 Biophysical Basis of Glomerular Filtration Roland C. Blantz and Scott Thomson 22 Glomerular Structure and Cell Biology Susan Quaggin 23 Function of the Juxtaglomerular Apparatus Jurgen Schnermann and Hayo Castrop 24 Renal Cortical & Medullary Microcirculations Thomas L. Pallone 25 Molecular and Cellular Mechanisms of Kidney Development Sanjay K. Nigam and Kevin T. Bush 26 Molecular and Cellular Mechanisms of Glomerular Capilary Development Jeffrey H. Miner and Dale R. Abrahamson 27 Postnatal Renal Development Michael Baum 28 Renal Hyperplasia and Hypertrophy Stuart J. Shankland 29 Stem Cells Qais Al-Awqati and Juan Oliver Section 3: Fluid and Electrolyte Regulation and Dysregulation 30 Epithelial Na+ Channels Thomas R. Kleyman 31 Anion Channels William B. Guggino 32 NaCL Co-transporters Gerardo Gamba 33 Sodium and Chlorid Transport Alan M. Weinstein 34 Sodium Chloride Transport in the Loop of Henle, Distal Convoluted Tubule, and Collecting Duct Gerardo Gamba and Laurent Schild 35 Mineralocorticoid Action in the Aldosterone-Sensitive Distal Nephron Johannes Loffing and Oliver Staub 36 Inherited Disorders of Renal Salt Homeostasis: Insights From Molecular Genetics Studies Rick Lifton 37 Natriuretic Hormones David L. Vesely 38 Physiology & Pathophysiology of Sodium Retention and Wastage Biff F. Palmer, Donald W. Seldin and Robert J. Alpern 39 Physiology of Hypertension John E. Hall 40 Physiology & Pathophysiology of Diuretic Action David H. Ellison 41 Aquaporin Water Channels in Mammalian Kidney Soren Nielsen 42 Thirst and Vasopressin Gary L. Robertson 43 The Urine Concentrating Mechanism and Urea Transporters Jeff M. Sands and Harold Layton 44 Hyponatremia Richard H. Sterns 45 Hypernatremic States Laurence Chan and Chris Rivard 46 Polyuria and Diabetes Insipidus Daniel G. Bichet 47 The Molecular Biology of Renal Potassium Channels Wenhui Wang and Chou Long Huang 48 Extrarenal Potassium Metabolism Robert M. Rosa 49 Regulation of Potassium Excretion Gerhard Giebisch and Lisa Satlin 50 Potassium Deficiency Giovambattista Capasso, Miriam Zacchia and Francesco Trepiccione 51 Clinical Disorders of Hyperkalemia Mitchell Halperin and Kamel 52 Control of Intracellular pH Walter F. Boron and Mark Bevensee 53 Sodium-Coupled Bicarbonate Transporters Ira Kurtz 54 The SLC4 Anion Exchanger Gene Family Seth Alper 55 Cellular Mechanisms of Renal Tubular Acidification Patricia Preisig, L. Lee Hamm and Robert Alpern 56 Chemoreceptors, Breathing, and pH Eugene Nattie 57 Renal Ammonium Ion Production and Excretion Norman P. Curthoys 58 Clinical Syndromes of Metabolic Alkalosis Orson Moe, Robert J. Alpern and Donald W. Seldin 59 Clinical Syndromes of Metabolic Acidosis Reto Krapf, Donald W. Seldin and Robert J. Alpern 60 Respiratory Alkalosis and Acidosis Horacio J Adrogue and Nicolaos Madias 61 Mechanisms and Disorders of Magnesium Metabolism Karl P. Schlingmann and Martin Konrad 62 Calcium Channels René J.M. Bindels and Joost Hoenderop 63 The Calcium-Sensing Receptor Edward Brown 64 Renal Calcium Metabolism Peter A. Friedman and Jose Bernardo 65 The Hormonal Regulation of Calcium Metabolism Rajiv Kumar 66 Disorders of Calcium Metabolism John Wysolmerski and Cristina Dumitru 67 Pathogenesis and Treatment of Nephrolithiasis Fredric L. Coe, Elaine Worcester and Andrew Evan 68 Proximal Tubular Handling of Phosphate Heini Murer, Jurg Biber, Nati Hernando, and Ian Forster 69 Clinical Disturbances of Phosphate Homeostasis Rajiv Kumar 70 Glucose Reabsorption in the Kidney Ernest M. Wright 71 Amino Acids, Oligopeptides, and Hyperaminoacidurias Francois Verrey, Simone R. Camargo, Victoria Makrides, Robert Kleta 72 Organic Anion and Cation Transporters in Renal Elimination of Drugs Gerhard Burckhardt and Herman Koepsell 73 Renal Filtration, Transport, and Metabolism of Albumin and Albuminuria Erik I. Christensen, Rikke Nielsen, Henrik Birn Section 4: Pathophysiology of Renal Disease 74 Physiologic Principles in the Clinical Evaluation of Electrolyte, Water, and Acid-Base Disorders Daniel Batlle 75 Biomarkers of Assessment of Renal Function (AKI/CKD) Prasad Devarajan 76 Pathophysiology of Acute Kidney Injury Bruce A Molitoris and Asif Sharfuddin 77 Ischemic Renal Disease William L. Henrich, Lance Dworkin, and Christopher Cooper 78 Pathophysiology and Pathogenesis of Diabetic Nephropathy Fuad N. Ziyadeh 79 Renal Failure in Cirrhosis Robert W. Schrier and Pere Gines 80 Autosomal Dominant Polycystic Kidney Disease and Inherited Cystic Diseases Stefan Somlo 81 Renal Physiology and Disease in Pregnancy Ananth Karunmanchi 82 Immune-Mediated and Other Glomerular Diseases John R. Sedor and Mike Madaio 83 Immunologic Mechanisms of Vasculitis J. Charles Jennette, Jonathan Homeister, Ronald J. Falk 84 Genetic Abnormalities in Glomerular Function Clifford E Kashtan and Yoav Segal 85 Cellular Mechanisms of Drug Nephrotoxicity Zoltán Huba Endre and Robert Walker 86 Role of Glomerular Pressure in Progression Roberto Zatz 87 Role of Protinuria in Progression Giuseppe Remuzzi 88 The Inflammatory Response to Ischemic Acute Renal Injury Christopher Y. Lu 89 Oxidants in Progressive Kidney Disease Sudhir Vithalbhai Shah 90 Chronic Kidney Disease William E. Mitch 91 Mineral Metabolism and Bone L. Darryl Quarles 92 Hematopoiesis and the Kidney Armin Kurtz 93 Electrolyte Disturbances in Dialysis Biff Palmer 94 Homeostasis of Solute and Water by the Transplanted Kidney J. Harold Helderman 95 Disposition and Dose Requirements of Drugs in renal Insufficiency D. Craig Brater, Kathleen Giacomini, Claire Weiss, Par Matsson

• ISBN: 978-0-12-381462-3
• Editorial: Academic Press
• Encuadernacion: Cartoné
• Páginas: 3290
• Fecha Publicación: 16/01/2013
• Nº Volúmenes: 1
• Idioma: Inglés