Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives. This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry. Reviews the most current developments and future perspectives of imidazole on different disease therapies to achieve the ultimate goal of disease eradication Discusses the role of imidazole in contemporary science, technological innovation, drug development, critical challenges and future research directions Covers emerging trends on different eco-benign pathways to synthesize imidazole derivatives for the development of simpler synthetic protocols INDICE: 1. Imidazole and its Derivatives: Introduction and Synthetic Aspects2. Biological Profile of Imidazole based Compounds as Anti-Cancer Agents3. Recent Advancements on Imidazole containing Heterocycles as Anti-Tubercular Agents4. Imidazole Derivatives: Impact and Prospects in Anti-Viral Drug Discovery5. Imidazole Heterocycles: Therapeutically Potent Lead Compounds as Anti-Microbials6. Imidazole containing Heterocycles as Antioxidants7. Miscellaneous Biological Activity Profile of Imidazole Based Compounds: An Aspirational Goal for Medicinal Chemistry8. Imidazole Based Drugs and Drug Discovery: Present and Future Perspectives
- ISBN: 978-0-323-85479-5
- Editorial: Elsevier
- Encuadernacion: Rústica
- Páginas: 372
- Fecha Publicación: 06/12/2021
- Nº Volúmenes: 1
- Idioma: Inglés